SURVIVE AND THRIVE, SMARTGUIDE

SmartGuide’s three prediction layers, a teaching resource

A one-page resource for clinicians and educators onboarding people onto the Accu-Chek SmartGuide. Each of the three prediction layers does a different job. Teach them in this order, and the wearer goes home with a usable mental model rather than three blinking icons. Designed to be printed at A4 and slipped into the SmartGuide group session pack.

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The frame to teach with

None of these layers prevents an event. Each gives an earlier window to act. The three models are independent (Herrero 2024, J Diabetes Sci Technol): a 30-minute hypo classifier, a 2-hour glucose forecast curve, and a 9pm-to-2am overnight risk score. They share the CGM data; they do not share each other’s logic. Wearers who understand the time horizons act on each appropriately. Wearers who do not, end up either over-trusting the 2-hour worm or under-trusting the overnight RAG light.

Layer 1, the active safety net

Low Glucose Predict, 30-minute hypo classifier

Low Glucose Predict, 30 minute lead time The alarm fires at the present moment when the model classifies a high hypo-risk window. From that moment, the wearer has approximately 30 minutes of lead time before the predicted low reaches 3.9 mmol/L. 8 6 3.9 2 mmol/L Now alarm fires +10 min +20 min +30 min predicted low ! 30-minute lead time
The alarm fires now, the moment the model classifies the next 30 minutes as high hypo-risk. From the alarm, the wearer has approximately 30 minutes of lead time before the predicted low crosses 3.9 mmol/L. The lead time is the value the layer adds; the alarm itself is the start of the window, not the end of it.

What it does

Classifies the next 30 minutes as high-risk or not for hypoglycaemia. When high-risk, an alarm fires.

What it does not do

It does not predict the size or depth of the low; it does not catch every event (sensitivity is not 100%). It is reactive, not preventive.

When to teach it

First, before either of the other two layers. This is the active safety net the wearer will rely on while learning the system.

What the wearer sees

An alarm on the SmartGuide app, not the Predict app. The Predict app holds the longer-horizon layers.

What to do when it fires

Finger prick to confirm if uncertain, treat per usual hypo plan, plan the next 30 minutes (driving, meeting, sleep). Re-check after the response window.

Teaching pitfall

Wearers who silenced “predictive low” alerts on previous CGMs because they fired too often. The SmartGuide LGP fires meaningfully less; ask them to keep it on for two weeks before deciding.

Layer 2, action and awareness

Glucose Predict, 2-hour forecast curve

Glucose Predict, mean line with 50 percent confidence interval error bars A mean predicted glucose trace from now to 2 hours, with vertical 50 percent confidence interval error bars at six 15-minute intervals. Error bars are short at 15 to 45 minutes (high confidence, action window) and widen materially at 60 minutes and beyond (lower confidence, awareness window). 10 8 6 4 mmol/L Action window, Parkes A+B 99.3% Awareness window, Parkes A+B 96.3% at 2 h Now +15 min +45 min +60 min +90 min +105 min +2 h Mean predicted glucose 50% confidence interval
The Glucose Predict layer outputs a mean predicted glucose curve with a 50% confidence interval. Error bars are short at 15 to 45 minutes (high confidence, the action window) and widen sharply at 60 minutes and beyond (lower confidence, the awareness window). Parkes Error Grid A+B agreement is 99.3% at 45 minutes and 96.3% at 2 hours (Herrero 2024). The widening of the error bars is the value of the layer; it teaches the wearer where to act and where only to plan.

What it does

Projects a glucose trace 2 hours forward, with a 50% confidence band drawn around it. Refreshes every 5 minutes.

What it does not do

It does not see meals or insulin doses the wearer has not entered. It does not account for alcohol, exercise, or illness. A wide band means low confidence.

When to teach it

After the LGP. Frame it as “the curve you plan around for the next hour, the curve you act on for the next forty-five minutes”. The split is the teach.

What the wearer sees

The Predict app shows the trace as a coloured worm with a shaded band. Narrow band, high confidence. Wide band, low confidence.

What to do when it lights up

0 to 45 min: act on the curve direction (eat ahead of a low, defer a correction if a fall is shown). 45 min to 2 h: plan around it (meeting timing, drive, exam, run).

Teaching pitfall

Selling the 2-hour mark as reliable. It is not. Wearers who treat the 2-hour endpoint as actionable will be disappointed quickly, and the disappointment is the form factor of a sensor falling out of routine wear.

Layer 3, the night plan

Night Low Predict, overnight risk score

Night Low Predict RAG dial A semicircular accelerometer-style gauge with red, amber, and green zones. A needle points to the wearer’s current overnight low-risk reading. Tick marks at 0, 25, 50, 75, and 100 percent risk. Below the dial, a panel notes the model’s discrimination is stronger for the first half of the night than the second. 0% 25% 75% 100% GREEN AMBER RED Night Low Predict, RAG output probability of nocturnal hypoglycaemia, 9pm to 7am AMBER, re-check in 20 min model uncertainty rising First half of night, ROC AUC 0.902 (strong) Second half of night, ROC AUC 0.730 (directional)
The Night Low Predict layer renders a Red, Amber, or Green output, shown here as an accelerometer-style dial. Below the dial, the model’s discrimination is stronger for the first half of the night (ROC AUC 0.902) than the second (0.730; Herrero 2024). The asymmetry should be taught at onboarding; a red light at 1am and a red light at 4am are not the same signal.

What it does

Issues a Red, Amber, or Green prediction of overnight low risk between 9pm and 2am, refreshable every 20 minutes. Personalises over ~28 days of input data.

What it does not do

It is a population-level confidence band, not a personal probability. It misses approximately 45% of overnight hypoglycaemia events at the published threshold; LGP remains the active safety net during the night.

When to teach it

Third. The wearer should already trust the LGP alarm and the GP curve. The night plan is what unlocks confidence to sleep.

What the wearer sees

A Red, Amber, or Green indicator before bed. Re-requestable every 20 minutes until 2am.

What to do when it lights up

Red, first half: fast carbohydrates before bed are the option most aligned with the risk (discuss with care team). Red, second half: lower model confidence, conversation about protein, slow-acting carbohydrates, or a temporary basal reduction (if on a pump). Amber: re-check in 20 minutes, watch for trend.

Teaching pitfall

Treating both halves of the night identically. The ROC AUC asymmetry (0.902 vs 0.730) means a red light at 1am and a red light at 4am are not the same signal. Land the asymmetry at onboarding.

Teaching order at a glance

Day 0, the group onboarding session. Layer 1 first, framed as the active safety net. Layer 2 second, with the 45-minute action / awareness split landed concretely. Layer 3 third, with the night-half asymmetry named.

Day 1, the calibration day. Two paired finger-prick calibrations at approximately 12 and 14 hours after insertion. The conversation about finger pricking is part of the teach, not an inconvenience to apologise for. After day one, no further finger pricks are needed.

Days 2 to 28, the personalisation period. Wearers should not draw conclusions from the first few nights. Night Low Predict needs the input data to reach its full personalised accuracy. The first month is the learning month for the system, not just for the wearer.

Day 14 onward, the end-of-wear drop. Accuracy holds reasonably (Mader 2024, 85.9% within plus or minus 20/20 on days 13 to 14 versus 92.8% on day 2). Schedule the next sensor before the current one ends.

About this resource

Produced alongside Episode 40 of the GNL Podcast with Amy Jolley (Lead Educator, Diabetes Technology Network UK; Highly Specialised Dietitian, Salford NHS Foundation Trust). Evidence audited against the GNL Grace wiki (Herrero 2024, Mader 2024). Independent of Roche Diagnostics. This content is for educational exploration only. It describes average responses and general principles. It is not medical advice and cannot replace individual clinical guidance from your diabetes care team.

SmartGuide device guide · Episode 40 show notes · All GNL resources

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